NONOXYNOL-9
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 617.0 | 4.5 | 1 | 10 | 103.0 | 35 | 0.82 |
- CAS
- 26027383
- UNII
- 48Q180SH9T
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 26 ZINC catalogs
Known Active Genes
This compound has been observed to have activity at 10μM or less against the following gene(s).
| Name | Description | Classification |
|---|---|---|
| SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter / Electrochemical-Transporter |
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter / Electrochemical-Transporter |
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT02309554 | 2014-12-01 | Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel | Phase 1 | Recruiting |
| NCT01593124 | 2012-05-01 | Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation | Phase 2 | Completed |
| NCT01232803 | 2010-10-01 | Rectal Safety and Acceptability Study of Tenofovir 1% Gel | Phase 1 | Completed |
| NCT00389311 | 2007-04-01 | A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides | Phase 0 | Completed |
| NCT00274261 | 2004-06-01 | Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol® | Phase 3 | Completed |
| NCT00692952 | 2004-03-01 | Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial | Phase 2 | Completed |
| NCT00000926 | 2001-02-01 | A Study of Nonoxynol-9 (N-9) and HIV Infection | Phase 3 | Completed |
| NCT00000929 | 1999-07-01 | A Study of the Effects of Advantage 24 on the Rectum | Phase 1 | Completed |