BUTYRIC ACID

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
87.0 -0.5 0 2 40.0 2 0.75
CAS
107926
UNII
40UIR9Q29H
SYNONYMS
ZINC ID(s)
Availability
Present in 82 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
HDAC3 Histone deacetylase 3 Epigenetic Regulator / Epigenetic-E

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT01561508 2012-06-01 Effect of GABA Supplementation in the Progression of Type 1 Diabetes in Children Phase 2 Withdrawn
NCT01536483 2012-02-01 Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams Phase 2/Phase 3 Recruiting
NCT01526876 2011-11-01 The Effect of Clevidipine on Intracranial Pressure and Cerebral Perfusion Pressure (CCP) in Brain Injured Patients Phase 4 Withdrawn
NCT02173808 2011-05-01 A Phase I Study to Evaluate the PK and PD of a Single Injection of Levonorgestrel Butanoate for Female Contraception Phase 1 Completed
NCT01042574 2010-05-01 The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy Phase 4 Recruiting
NCT00978822 2009-09-01 Safety and Efficacy Study of Clevidipine to Control Hypertension in Patients Admitted With Aneurysmal Subarachnoid Hemorrhage Phase 2 Recruiting
NCT00917826 2008-09-01 Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies Phase 2 Terminated
NCT01567995 2008-02-01 Randomised, Double-blind, Placebo-controlled Study of Topical Clobetasone Butyrate 0.05% Cream in Subjects With Eczema for Two Weeks to Evaluate the Efficacy and Safety Phase 3 Completed
NCT00693693 2006-11-01 Adherence to Topical Hydrocortisone 17-Butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis Phase 4 Active, Not Recruiting
NCT00800930 2005-01-01 Therapeutic Induction of Endogenous Antibiotics Phase 2 Completed
NCT00801957 2003-03-01 Equivalence of the Response to Vaccination of Tacrolimus Ointment to a Steroid Ointment Regimen in Children With Atopic Dermatitis Phase 2 Completed
NCT00006136 1999-03-01 Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia Phase 2 Completed
NCT00004412 1997-09-01 Phase II Randomized Trial of Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers Phase 2 Recruiting
NCT00006340 1994-12-01 Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus Phase 1 Completed

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Transdermal Patch, Controlled Release

More Information

Usage Over Time

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