Trisenox

Product manufactured by Cephalon, Inc.

Application Nr Approved Date Route Status External Links
NDA021248 None Intravenous None Google , Wikipedia , PubMed , DailyMed , Raw OpenFDA , ECHA , ToxNet , JECFA , FAO , 21 CFR

Indications and Purposes

1 Indications And Usage Trisenox Is An Arsenical Indicated: In Combination With Tretinoin For Treatment Of Adults With Newly-Diagnosed Low-Risk Acute Promyelocytic Leukemia (Apl) Whose Apl Is Characterized By The Presence Of The T(15;17) Translocation Or Pml/rar-Alpha Gene Expression. ( 1.1 ) For Induction Of Remission And Consolidation In Patients With Apl Who Are Refractory To, Or Have Relapsed From, Retinoid And Anthracycline Chemotherapy, And Whose Apl Is Characterized By The Presence Of The T(15;17) Translocation Or Pml/rar-Alpha Gene Expression. ( 1.2 ) 1.1 Newly-Diagnosed Low-Risk Apl Trisenox Is Indicated In Combination With Tretinoin For Treatment Of Adults With Newly-Diagnosed Low-Risk Acute Promyelocytic Leukemia (Apl) Whose Apl Is Characterized By The Presence Of The T(15;17) Translocation Or Pml/rar-Alpha Gene Expression. 1.2 Relapsed Or Refractory Apl Trisenox Is Indicated For Induction Of Remission And Consolidation In Patients With Apl Who Are Refractory To, Or Have Relapsed From, Retinoid And Anthracycline Chemotherapy, And Whose Apl Is Characterized By The Presence Of The T(15;17) Translocation Or Pml/rar-Alpha Gene Expression.

All Formulated Excipients (0 Total)

None

Active Ingredients ( 1 Total)

Name Structure ZINC ID(s)
1. Arsenic Trioxide

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